Hye-Won Kang*, Luan Nguyen, Songon An, and Minjoung Kyoung* “Mechanistic insights into condensate formation of human phosphofructokinase by stochastic modeling approaches” Scientific Reports (2024) 14, 19011 and bioRxiv (2022) doi.org/10.1101/2022.06.27.497813
Miji Jeon, Danielle L. Schmitt, Minjoung Kyoung, and Songon An* “Size-specific modulation of a multienzyme glucosome assembly during the cell cycle” ACS Bio & Med Chem Au (2023) 3, 461-470 (Journal’s Cover Story) and bioRxiv (2022)
Danielle L. Schmitt, Patricia Dranchak, Prakash Parajuli, Dvir Blivis, Ty Voss, Casey L. Kohnhorst, Minjoung Kyoung, James Inglese, and Songon An* “High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells” PLoS One (2023) 18, e0289707, and bioRxiv (2022)
Erin L. Kennedy, Miji Jeon, Farhan Augustine, Krishna M. Chauhan, Songon An, and Minjoung Kyoung* “Functional regulation of 4D metabolic network between multienzyme glucosome condensates and mitochondria in living cells” bioRxiv (2022)
Miji Jeon, Krishna M. Chauhan, Gregory L. Szeto, Minjoung Kyoung, and Songon An* “Subcellular regulation of glucose metabolism through multienzyme glucosome assemblies by EGF-ERK1/2 signaling pathways” J. Biol. Chem. (2022) 298, 101675
Songon An*, Prakash Parajuli, Erin L. Kennedy, and Minjoung Kyoung* “Multi-dimensional fluorescence live-cell imaging for glucosome dynamics in living human cells” Methods in Molecular Biology (2022) 2487, 15-26 (Accepted on May 15, 2021, Published Online on June 11, 2022) doi: 10.1007/978-1-0716-2269-8_2
Songon An*, Danielle L. Schmitt, James Inglese, Patricia Dranchak “Method of Identifying a compound which affects the multienzyme metabolic assembly of glucose metabolism and its association with cell cycle progression in cancer cells” Patent (2020), US20190391135A1 (Pub: Dec. 26, 2019), US16/452,767 (Feb 7, 2020; Pending)
Songon An*, Miji Jeon, Erin L. Kennedy, and Minjoung Kyoung* “Phase-Separated Condensates of Metabolic Complexes in Living Cells: Purinosome and Glucosome“ Methods in Enzymology (2019) 628, 1-17 https://doi.org/10.1016/bs.mie.2019.06.013
Danielle L. Schmitt, Anand Sundaram, Miji Jeon, Bao Tran Luu, and Songon An* “Spatial Alterations of de novo Purine Biosynthetic Enzymes by Akt-independent PDK1 Signaling Pathways” PLoS One (2018) 13, e0195989.
Miji Jeon, Hye-Won Kang*, and Songon An* “A Mathematical Model of Enzyme Clustering in Glucose Metabolism” Scientific Reports (2018) 8, 2696.
Danielle L. Schmitt and Songon An* “Spatial Organization of Metabolic Enzyme Complexes in Cells” Biochemistry (2017) 56, 3184-3196. (Invited)
Casey L. Kohnhorst^, Minjoung Kyoung^, Miji Jeon, Danielle L. Schmitt, Erin L. Kennedy, Julio Ramirez, Syrena M. Bracey, Bao Tran Luu, Sarah J. Russell, and Songon An* “Identification of a Multienzyme Complex for Glucose Metabolism in Living Cells” J. Biol. Chem. (2017) 292, 9191-9203. (Published Online on April 19, 2017)
- The editors of JBC informed Dr. An that “Your paper was viewed 468 times on the JBC website in April and May.” (June 29, 2017).
- This article is also recommended by the faculty of 1000 (F1000) (August 4, 2017).
- This article is recently selected for a special virtual issue of JBC that highlights “new insights in the cellular, tissue and whole body integration of carbohydrate metabolism and energy balance” (September 2019).
Songon An and Klaus Pors “Cancer Metabolism” AACR-CICR* Newsletter, June 2016 (*AACR-CICR: Chemistry in Cancer Research Working Group at the American Association for Cancer Research)
Danielle L. Schmitt, Yun-ju Cheng, Junyong Park, and Songon An* “Sequestration-mediated downregulation of de novo purine biosynthesis by AMPK” ACS Chemical Biology (2016) 11, 1917- 1924
Casey L. Kohnhorst, Danielle L. Schmitt, Anand Sundaram, and Songon An* “Subcellular Functions of Proteins under Fluorescence Single-cell Microscopy” BBA – Proteins and Proteomics (Special Issue of Physilogical Enzymology) (2016) 1864, 77-84 (Invited)
Minjoung Kyoung, Sarah J. Russell, Casey L. Kohnhorst, Nopondo N. Esemoto, and Songon An* “Dynamic architecture of the purinosome involved in human de novo purine biosynthesis” Biochemistry (2015) 54, 870-880
Jarrod B. French, Hong Zhao, Songon An, Sherry Niessen, Yijun Deng, Benjamin F. Cravatt, and Stephen J. Benkovic* “Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome” Proc. Natl. Acad. Sci. USA (2013) 110, 2528-2533
Yijun Deng, Jongsik Gam, Jarrod B. French, Hong Zhao, Songon An, and Stephen J. Benkovic* “Mapping Protein-Protein Proximity in the Purinosome” J. Biol. Chem. (2012) 287, 36201-36207
Florence Verrier, Songon An, Ye Fang, and Stephen J. Benkovic “Methods to identify targets and molecules regulating purinosomes and their uses” Patent (2012) Application No. PCT/US2011/043930. WO/2012/015599
Florence Verrier^, Songon An^, Ann M. Ferrie, Haiyan Sun, Minjoung Kyoung, Huayun Deng, Ye Fang and Stephen J. Benkovic* “GPCRs regulate the assembly of a multienzyme complex for purine biosynthesis” Nature Chem. Biol. (2011) 7, 909-915 *Co-first authors
- Nature Chemical Biology – News and Views:
- Nature Structural and Molecular Biology – Research Highlights:
Byung Ran So, Songon An, Sandeep Kumar, Mom Das, Daniel A. Turner, Christopher M. Hadad and Karin Musier-Forsyth* “Substrate-mediated fidelity mechanism ensures accurate decoding of proline codons” J. Biol. Chem. (2011) 286, 31810-31820
Songon An, Yijun Deng, John W. Tomsho, Minjoung Kyoung, and Stephen J. Benkovic* “Microtubule-assisted Mechanism forFunctional Metabolic Macromolecular Complex Formation” Proc. Natl. Acad. Sci. USA (2010) 107, 12872-12876
Anjali Mascarenhas, Songon An, Abbey E. Rogen, Susan Martinis and Karin Musier-Forsyth* “Fidelity Mechanism of Aminoacyl-tRNA Synthetases” in Protein Engineering (2009) Eds. Uttam L. RajBhandary and Caroline Köhrer, Springer-Verlag Berlin Heidelberg, ISBN: 978-3-540-70937-4, e-ISBN: 978-3-540-70941-1, pp155-2035.
Songon An*, Ravindra Kumar, Erin D. Sheets*, and Stephen J. Benkovic* “ReversibleCompartmentalization of de novo Purine Biosynthetic Complexes in Living Cells” Science (2008) 320, 103-106
Brian Burke, Songon An and Karin Musier-Forsyth* “Functional Guanine-Arginine Interaction Between tRNAPro and Prolyl-tRNA Synthetase that Couples Binding and Catalysis” BBA – Proteins and Proteomics (2008) 1784, 1222-1225
Songon An, George Barany and Karin Musier-Forsyth* “Evolution of Acceptor Stem tRNA Recognition by Class II Prolyl-tRNA Synthetase” Nucleic Acids Research (2008) 36, 2514-2521
Songon An and Karin Musier-Forsyth* “Cys-tRNAPro Editing by Haemophilus influenzae YbaK via a Novel Synthetase-YbaK-tRNA Ternary Complex” J. Biol. Chem. (2005) 280, 34465-34472
Songon An and Karin Musier-Forsyth* “Trans-editing of Cys-tRNAPro by Haemophilus influenzae YbaK protein” J. Biol. Chem. – Accelerated Publication (2004) 279, 42359-42362
* Corresponding Authors ^ Equal Contributions